PDBe 3fal

X-ray diffraction
2.36Å resolution

Function and Biology Details

Structure analysis Details

Assemblies composition:
hetero tetramer
hetero dimer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Oxysterols receptor LXR-alpha Chains: B, D
Molecule details ›
Chains: B, D
Length: 266 amino acids
Theoretical weight: 30.62 KDa
Source organism: Mus musculus
Expression system: Escherichia coli
UniProt:
  • Canonical: Q9Z0Y9 (Residues: 200-445; Coverage: 55%)
Gene names: Lxra, Nr1h3
Sequence domains: Ligand-binding domain of nuclear hormone receptor
Structure domains: Retinoid X Receptor
Retinoic acid receptor RXR-alpha Chains: A, C
Molecule details ›
Chains: A, C
Length: 242 amino acids
Theoretical weight: 27.11 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P19793 (Residues: 225-462; Coverage: 52%)
Gene names: NR2B1, RXRA
Sequence domains: Ligand-binding domain of nuclear hormone receptor
Structure domains: Retinoid X Receptor

Ligands and Environments

2 bound ligands:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 32-ID
Spacegroup: C2
Unit cell:
a: 123.212Å b: 90.002Å c: 101.311Å
α: 90° β: 111.88° γ: 90°
R-values:
R R work R free
0.222 0.219 0.278
Expression system: Escherichia coli