PDBe 3f81

X-ray diffraction
1.9Å resolution

Function and Biology Details

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Dual specificity protein phosphatase 3 Chains: A, B
Molecule details ›
Chains: A, B
Length: 183 amino acids
Theoretical weight: 20.28 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P51452 (Residues: 3-185; Coverage: 99%)
Gene names: DUSP3, VHR
Sequence domains: Dual specificity phosphatase, catalytic domain
Structure domains: Protein tyrosine phosphatase superfamily

Ligands and Environments

1 bound ligand:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU FR-E SUPERBRIGHT
Spacegroup: P21
Unit cell:
a: 50.406Å b: 59.186Å c: 60.656Å
α: 90° β: 98.36° γ: 90°
R-values:
R R work R free
0.18 0.178 0.219
Expression system: Escherichia coli