PDBe 3efi

X-ray diffraction
1.75Å resolution

Carbonic anhydrase activators: Kinetic and X-ray crystallographic study for the interaction of d- and l-tryptophan with the mammalian isoforms I-XIV

Released:

Function and Biology Details

Reaction catalysed:
H(2)CO(3) = CO(2) + H(2)O. 
Biochemical function:
Biological process:
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Carbonic anhydrase 2 Chain: A
Molecule details ›
Chain: A
Length: 260 amino acids
Theoretical weight: 29.29 KDa
Source organism: Synthetic construct
Expression system: Not provided
Structure domains: Carbonic Anhydrase II

Ligands and Environments

3 bound ligands:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: OXFORD DIFFRACTION ENHANCED ULTRA
Spacegroup: P21
Unit cell:
a: 42.07Å b: 41.32Å c: 72.05Å
α: 90° β: 104.4° γ: 90°
R-values:
R R work R free
0.191 0.189 0.222
Expression system: Not provided