PDBe 3e3p

X-ray diffraction
2Å resolution

Glycogen synthase kinase from Leishmania major

Released:
Source organism: Leishmania major
Entry authors: Arakaki TL, Merritt EA

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Putative glycogen synthase kinase Chains: A, B
Molecule details ›
Chains: A, B
Length: 360 amino acids
Theoretical weight: 41.2 KDa
Source organism: Leishmania major
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q4QE15 (Residues: 1-355; Coverage: 100%)
Gene names: GSK3, LMJF_18_0270
Sequence domains: Protein kinase domain
Structure domains:

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 23-ID-D
Spacegroup: C2221
Unit cell:
a: 70.205Å b: 155.717Å c: 158.768Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.226 0.224 0.271
Expression system: Escherichia coli BL21(DE3)