› › Structure analysis

Crystal structure of the parasite protesase inhibitor chagasin in complex with papain

X-ray diffraction
1.86Å resolution
PDB entry 3e1z coloured by chain, front view.
PDB entry 3e1z coloured by chain, side view.
PDB entry 3e1z coloured by chain, top view.
Source organisms:
Assembly composition:
hetero dimer (preferred)
Entry contents: 2 distinct polypeptide molecules

Quick links

Assemblies

Assembly 1 (preferred)
Download    3D Visualisation
Assembly Name: Chagasin and Papain
hide full assembly name
Multimeric state: hetero dimer
Accessible surface area: 13800.42 Å2
Buried surface area: 3436.76 Å2
Dissociation area: 925.23 Å2
Dissociation energy (ΔGdiss): 4.34 kcal/mol
Dissociation entropy (TΔSdiss): 11.47 kcal/mol
Symmetry number: 1
PDBe Complex ID: PDB-CPX-133549

Macromolecules

Chagasin
Chain: A
Length: 110 amino acids
Theoretical weight: 12.05 KDa
Source organism: Trypanosoma cruzi
Expression system: Escherichia coli
UniProt:
  • Canonical: Q966X9 (Residues: 1-110; Coverage: 100%)
Gene name: cha
Pfam: Chagasin family peptidase inhibitor I42
InterPro:
CATH: Immunoglobulin-like
Chagasin in PDB entry 3e1z, assembly 1, front view.
Chagasin in PDB entry 3e1z, assembly 1, side view.
Chagasin in PDB entry 3e1z, assembly 1, top view.
Molecule details ›

Search similar proteins

Papain
Chain: B
Length: 212 amino acids
Theoretical weight: 23.45 KDa
Source organism: Carica papaya
UniProt:
  • Canonical: P00784 (Residues: 134-345; Coverage: 65%)
Pfam: Papain family cysteine protease
InterPro:
CATH: Cysteine proteinases
Papain in PDB entry 3e1z, assembly 1, front view.
Papain in PDB entry 3e1z, assembly 1, side view.
Papain in PDB entry 3e1z, assembly 1, top view.
Molecule details ›

Search similar proteins

Quick links