PDBe 3dxn

X-ray diffraction
2.17Å resolution

Crystal structure of the calcium-dependent kinase from toxoplasma gondii, 541.m00134, kinase domain.

Released:
Source organism: Toxoplasma gondii
Entry authors: Wernimont AK, Lew J, Kozieradzki I, Cossar D, Wasney G, Lin YH, Hassani A, Ali A, Schapira M, Bochkarev A, Arrowsmith CH, Bountra C, Wikstrom M, Edwards AM, Hui R, Artz JD, Amani M, Structural Genomics Consortium (SGC)

Function and Biology Details

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Calmodulin-like domain protein kinase isoform 3 Chain: A
Molecule details ›
Chain: A
Length: 287 amino acids
Theoretical weight: 33.03 KDa
Source organism: Toxoplasma gondii
Expression system: Escherichia coli
UniProt:
  • Canonical: Q3HNM6 (Residues: 72-340; Coverage: 50%)
Sequence domains: Protein kinase domain
Structure domains:

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU FR-E+ SUPERBRIGHT
Spacegroup: I4
Unit cell:
a: 121.345Å b: 121.345Å c: 45.521Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.232 0.23 0.265
Expression system: Escherichia coli