PDBe 3d5f

X-ray diffraction
2.2Å resolution

Crystal Structure of PPAR-delta complex

Released:
Source organism: Homo sapiens
Entry author: Amano Y

Function and Biology Details

Structure analysis Details

Assemblies composition:
homo dimer
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Peroxisome proliferator-activated receptor delta Chains: A, B
Molecule details ›
Chains: A, B
Length: 267 amino acids
Theoretical weight: 30.57 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q03181 (Residues: 175-441; Coverage: 61%)
  • Best match: Q03181-2 (Residues: 175-359)
Gene names: NR1C2, PPARB, PPARD
Sequence domains: Ligand-binding domain of nuclear hormone receptor
Structure domains: Retinoid X Receptor

Ligands and Environments

1 bound ligand:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SPRING-8 BEAMLINE BL32B2
Spacegroup: P21
Unit cell:
a: 39.456Å b: 92.829Å c: 96.454Å
α: 90° β: 98.02° γ: 90°
R-values:
R R work R free
0.278 0.278 0.281
Expression system: Escherichia coli BL21(DE3)