PDBe 3cxl

X-ray diffraction
2.6Å resolution

Crystal structure of human chimerin 1 (CHN1)

Released:
Source organism: Homo sapiens
Entry authors: Shen L, Buck M, Tong Y, Tempel W, MacKenzie F, Arrowsmith CH, Edwards AM, Bountra C, Wilkstrom M, Bochkarev A, Park H, Structural Genomics Consortium (SGC)

Function and Biology Details

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
N-chimaerin Chain: A
Molecule details ›
Chain: A
Length: 463 amino acids
Theoretical weight: 53.8 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P15882 (Residues: 15-459; Coverage: 97%)
Gene names: ARHGAP2, CHN, CHN1
Sequence domains:
Structure domains:

Ligands and Environments

2 bound ligands:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 19-ID
Spacegroup: P62
Unit cell:
a: 152.187Å b: 152.187Å c: 69.529Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.267 0.266 0.3
Expression system: Escherichia coli