PDBe 3cwg

X-ray diffraction
3.05Å resolution

Unphosphorylated mouse STAT3 core fragment

Source organism: Mus musculus
Primary publication:
Crystal structure of unphosphorylated STAT3 core fragment.
Biochem. Biophys. Res. Commun. 374 1-5 (2008)
PMID: 18433722

Function and Biology Details

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Signal transducer and activator of transcription 3 Chains: A, B
Molecule details ›
Chains: A, B
Length: 562 amino acids
Theoretical weight: 64.42 KDa
Source organism: Mus musculus
Expression system: Escherichia coli BL21(DE3)
  • Canonical: P42227 (Residues: 127-688; Coverage: 73%)
Gene names: Aprf, Stat3
Sequence domains:
Structure domains:

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ALS BEAMLINE 8.3.1
Spacegroup: P3121
Unit cell:
a: 254.779Å b: 254.779Å c: 123.781Å
α: 90° β: 90° γ: 120°
R R work R free
0.25 0.25 0.268
Expression system: Escherichia coli BL21(DE3)