› 3cw3

X-ray diffraction
1.88Å resolution

Crystal structure of AIM1g1

Released:
DOI: 10.2210/pdb3cw3/pdb
PDB entry 3cw3 coloured by chain, front view.
PDB entry 3cw3 coloured by chain, side view.
PDB entry 3cw3 coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Exploring the limits of sequence and structure in a variant betagamma-crystallin domain of the protein absent in melanoma-1 (AIM1).
Aravind P, Wistow G, Sharma Y, Sankaranarayanan R
J Mol Biol 381 509-18 (2008)
PMID: 18582473

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-195244 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Beta/gamma crystallin domain-containing protein 1 Chain: A
Molecule details ›
Chain: A
Length: 96 amino acids
Theoretical weight: 10.82 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q9Y4K1 (Residues: 1022-1117; Coverage: 6%)
Gene names: AIM1, CRYBG1
Sequence domains: Beta/Gamma crystallin
Structure domains: Crystallins

Ligands and Environments

1 bound ligand:
Ligand GOL 1 x GOL
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU RUH3R
Spacegroup: P65
Unit cell:
a: 54.964Å b: 54.964Å c: 59.574Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.181 0.181 0.232
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

3 review citations

The human crystallin gene families.
Wistow G. (2012)
2 more

4 mentions without citation

Evolution of crystallins for a role in the vertebrate eye lens.
Slingsby et al. (2013)
3 more