PDBe 3crt

X-ray diffraction
1.9Å resolution

Structural characterization of an engineered allosteric protein

Released:

Function and Biology Details

Reaction catalysed:
RX + glutathione = HX + R-S-glutathione. 
Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Glutathione S-transferase class-mu 26 kDa isozyme Chain: A
Molecule details ›
Chain: A
Length: 214 amino acids
Theoretical weight: 25.06 KDa
Source organism: Schistosoma japonicum
Expression system: Escherichia coli
UniProt:
  • Canonical: P08515 (Residues: 1-214; Coverage: 98%)
Sequence domains:
Structure domains:

Ligands and Environments

1 bound ligand:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: BRUKER AXS MICROSTAR-H
Spacegroup: P43212
Unit cell:
a: 91.18Å b: 91.18Å c: 57.53Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.227 0.227 0.257
Expression system: Escherichia coli