PDBe 3coi

X-ray diffraction
2.09Å resolution

Crystal structure of p38delta kinase

Released:
Source organism: Homo sapiens
Entry authors: Atwell S, Burley SK, Houle A, Ramos A, Sauder JM, New York SGX Research Center for Structural Genomics (NYSGXRC)

Function and Biology Details

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Mitogen-activated protein kinase 13 Chain: A
Molecule details ›
Chain: A
Length: 353 amino acids
Theoretical weight: 40.65 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: O15264 (Residues: 2-352; Coverage: 96%)
Gene names: MAPK13, PRKM13, SAPK4
Sequence domains: Protein kinase domain
Structure domains:

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 31-ID
Spacegroup: P212121
Unit cell:
a: 66.271Å b: 71.305Å c: 97.933Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.208 0.208 0.242
Expression system: Escherichia coli BL21(DE3)