PDBe 3ckw

X-ray diffraction
1.96Å resolution

Crystal structure of sterile 20-like kinase 3 (MST3, STK24)

Source organism: Homo sapiens
Entry authors: Antonysamy SS, Burley SK, Buchanan S, Chau F, Feil I, Wu L, Sauder JM, New York SGX Research Center for Structural Genomics (NYSGXRC)

Function and Biology Details

Reaction catalysed:
ATP + a protein = ADP + a phosphoprotein. 
Biochemical function:
Biological process:
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Serine/threonine-protein kinase 24 36 kDa subunit Chain: A
Molecule details ›
Chain: A
Length: 304 amino acids
Theoretical weight: 34.57 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
  • Canonical: Q9Y6E0 (Residues: 31-323; Coverage: 66%)
Gene names: MST3, STK24, STK3
Sequence domains: Protein kinase domain
Structure domains:

Ligands and Environments

1 bound ligand:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 31-ID
Spacegroup: P21
Unit cell:
a: 47.43Å b: 56.368Å c: 61.55Å
α: 90° β: 112.69° γ: 90°
R R work R free
0.207 0.207 0.265
Expression system: Escherichia coli