PDBe 3cjw

X-ray diffraction
1.48Å resolution

Crystal structure of the human COUP-TFII ligand binding domain

Released:

Function and Biology Details

Structure analysis Details

Assemblies composition:
homo dimer
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
COUP transcription factor 2 Chain: A
Molecule details ›
Chain: A
Length: 244 amino acids
Theoretical weight: 27.31 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P24468 (Residues: 175-414; Coverage: 58%)
Gene names: ARP1, NR2F2, TFCOUP2
Sequence domains: Ligand-binding domain of nuclear hormone receptor
Structure domains: Retinoid X Receptor

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 5ID-B
Spacegroup: C2
Unit cell:
a: 97.854Å b: 47.762Å c: 43.128Å
α: 90° β: 100.87° γ: 90°
R-values:
R R work R free
0.168 0.168 0.238
Expression system: Escherichia coli BL21(DE3)