PDBe 3ciu

X-ray diffraction
3.5Å resolution

Site-Selective Glycosylation of Cysteine-93 beta on the Surface of Bovine Hemoglobin and its Application as a Novel Oxygen Therapeutic

Released:
Source organism: Bos taurus
Entry authors: Bhatt VS, Zhang Y, Sun G, Wang PG, Palmer AF

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:

Structure analysis Details

Assembly composition:
hetero tetramer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Hemoglobin subunit beta Chains: B, D
Molecule details ›
Chains: B, D
Length: 145 amino acids
Theoretical weight: 15.98 KDa
Source organism: Bos taurus
Expression system: Not provided
UniProt:
  • Canonical: P02070 (Residues: 1-145; Coverage: 100%)
Gene name: HBB
Sequence domains: Globin
Structure domains: Globins
Hemoglobin subunit alpha Chains: A, C
Molecule details ›
Chains: A, C
Length: 141 amino acids
Theoretical weight: 15.08 KDa
Source organism: Bos taurus
Expression system: Not provided
UniProt:
  • Canonical: P01966 (Residues: 2-142; Coverage: 99%)
Gene name: HBA
Sequence domains: Globin
Structure domains: Globins

Ligands and Environments

3 bound ligands:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU
Spacegroup: P212121
Unit cell:
a: 62.604Å b: 73.982Å c: 129.796Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.271 0.268 0.332
Expression system: Not provided