Assemblies
Assembly Name:
Transthyretin
Multimeric state:
homo tetramer
Accessible surface area:
19309.35 Å2
Buried surface area:
6230.25 Å2
Dissociation area:
1,357.85
Å2
Dissociation energy (ΔGdiss):
17.9
kcal/mol
Dissociation entropy (TΔSdiss):
12.7
kcal/mol
Symmetry number:
4
PDBe Complex ID:
PDB-CPX-136168
Assembly Name:
Transthyretin
Multimeric state:
homo dimer
Accessible surface area:
10976.43 Å2
Buried surface area:
1796.83 Å2
Dissociation area:
898.41
Å2
Dissociation energy (ΔGdiss):
7.36
kcal/mol
Dissociation entropy (TΔSdiss):
11.53
kcal/mol
Symmetry number:
2
PDBe Complex ID:
PDB-CPX-136167
Macromolecules
Chains: A, B
Length: 118 amino acids
Theoretical weight: 12.96 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
Pfam: HIUase/Transthyretin family
InterPro:
Length: 118 amino acids
Theoretical weight: 12.96 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
- Canonical: P02766 (Residues: 30-147; Coverage: 93%)
Pfam: HIUase/Transthyretin family
InterPro:
- Transthyretin/hydroxyisourate hydrolase domain
- Transthyretin/hydroxyisourate hydrolase domain superfamily
- Transthyretin/hydroxyisourate hydrolase
- Transthyretin, thyroxine binding site
- Transthyretin, conserved site