› 3cd4

X-ray diffraction
2.2Å resolution

REFINEMENT AND ANALYSIS OF THE FIRST TWO DOMAINS OF HUMAN CD4

Released:
DOI: 10.2210/pdb3cd4/pdb
PDB entry 3cd4 coloured by chain, front view.
PDB entry 3cd4 coloured by chain, side view.
PDB entry 3cd4 coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Refinement and analysis of the structure of the first two domains of human CD4.
Garrett TP, Wang J, Yan Y, Liu J, Harrison SC
J Mol Biol 234 763-78 (1993)
PMID: 8254672

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
Cellular component:
Sequence domains:
Structure domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-134559 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
T-cell surface glycoprotein CD4 Chain: A
Molecule details ›
Chain: A
Length: 182 amino acids
Theoretical weight: 20.2 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
  • Canonical: P01730 (Residues: 26-207; Coverage: 42%)
Gene name: CD4
Sequence domains:
Structure domains: Immunoglobulins

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Spacegroup: C2
Unit cell:
a: 84.23Å b: 30.65Å c: 88.94Å
α: 90° β: 118.43° γ: 90°
R-values:
R R work R free
0.197 0.197 not available
Expression system: Not provided

Quick links

Citations

4 review citations

The molecular structure of cell adhesion molecules.
Chothia et al. (1997)
3 more

13 mentions without citation

Thiol-Disulfide Exchange Reactions in the Mammalian Extracellular Environment.
Yi et al. (2016)
12 more