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PP2A-specific methylesterase apo form (PME)

X-ray diffraction
2Å resolution
PDB entry 3c5v coloured by chain, front view.
PDB entry 3c5v coloured by chain, side view.
PDB entry 3c5v coloured by chain, top view.
Source organism: Homo sapiens
Assembly composition:
monomeric (preferred)
Entry contents: 1 distinct polypeptide molecule

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Assemblies

Assembly 1 (preferred)
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Assembly Name: Protein phosphatase methylesterase 1
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Multimeric state: monomeric
Accessible surface area: 12661.69 Å2
Buried surface area: 0.0 Å2
Dissociation area: 0 Å2
Dissociation energy (ΔGdiss): 0 kcal/mol
Dissociation entropy (TΔSdiss): 0 kcal/mol
Symmetry number: 1
PDBe Complex ID: PDB-CPX-195260

Macromolecules

Protein phosphatase methylesterase 1
Chain: A
Length: 316 amino acids
Theoretical weight: 34.74 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q9Y570 (Residues: 39-386; Coverage: 82%)
Gene names: PME1, PP2593, PPME1, PRO0750
Pfam: Alpha/beta hydrolase family
InterPro:
CATH: alpha/beta hydrolase
Protein phosphatase methylesterase 1 in PDB entry 3c5v, assembly 1, front view.
Protein phosphatase methylesterase 1 in PDB entry 3c5v, assembly 1, side view.
Protein phosphatase methylesterase 1 in PDB entry 3c5v, assembly 1, top view.
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