PDBe 3c0h

X-ray diffraction
2.3Å resolution

CASK CaM-Kinase Domain- AMPPNP complex, P1 form

Released:
Source organism: Homo sapiens

Function and Biology Details

Reaction catalysed:
ATP + a protein = ADP + a phosphoprotein. 
Biochemical function:
Biological process:
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Peripheral plasma membrane protein CASK Chains: A, B
Molecule details ›
Chains: A, B
Length: 351 amino acids
Theoretical weight: 39.26 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21
UniProt:
  • Canonical: O14936 (Residues: 1-337; Coverage: 36%)
Gene names: CASK, LIN2
Sequence domains: Protein kinase domain
Structure domains:

Ligands and Environments

1 bound ligand:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: MPG/DESY, HAMBURG BEAMLINE BW6
Spacegroup: P1
Unit cell:
a: 55.387Å b: 59.675Å c: 61.086Å
α: 90° β: 105.57° γ: 105.63°
R-values:
R R work R free
0.191 0.188 0.239
Expression system: Escherichia coli BL21