PDBe 3bpf

X-ray diffraction
2.9Å resolution

Crystal Structure of Falcipain-2 with Its inhibitor, E64


Function and Biology Details

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Falcipain 2 Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 241 amino acids
Theoretical weight: 27.19 KDa
Source organism: Plasmodium falciparum
  • Canonical: Q9N6S8 (Residues: 244-484; Coverage: 50%)
Sequence domains: Papain family cysteine protease
Structure domains: Cysteine proteinases

Ligands and Environments

2 bound ligands:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRL BEAMLINE BL9-1
Spacegroup: C2221
Unit cell:
a: 143.778Å b: 167.81Å c: 177.758Å
α: 90° β: 90° γ: 90°
R R work R free
0.278 0.275 0.325