EC 3.4.15.1: Peptidyl-dipeptidase A
Reaction catalysed:
Release of a C-terminal dipeptide, oligopeptide-|-Xaa-Yaa, when Xaa is not Pro, and Yaa is neither Asp nor Glu. Thus, conversion of angiotensin I to angiotensin II, with increase in vasoconstrictor activity, but no action on angiotensin II.
Systematic name:
-
Alternative Name(s):
- ACE
- Angiotensin I-converting enzyme
- Angiotensin converting enzyme
- Carboxycathepsin
- DCP
- Dipeptidase
- Dipeptide hydrolase
- Dipeptidyl carboxypeptidase
- Dipeptidyl carboxypeptidase I
- Endothelial cell peptidyl dipeptidase
- Kininase II
- PDH
- Peptidase P
- Peptidyl dipeptidase A
- Peptidyl dipeptidase I
- Peptidyl dipeptidase-4
- Peptidyl dipeptide hydrolase
- Peptidyl-dipeptide hydrolase
- Peptidyldipeptide hydrolase
Protein family (Pfam)
InterPro annotation