PDBe 3bhy

X-ray diffraction
1.24Å resolution

Crystal structure of human death associated protein kinase 3 (DAPK3) in complex with a beta-carboline ligand

Released:

Function and Biology Details

Reaction catalysed:
ATP + a protein = ADP + a phosphoprotein. 
Biochemical function:
Biological process:
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Death-associated protein kinase 3 Chain: A
Molecule details ›
Chain: A
Length: 283 amino acids
Theoretical weight: 32.55 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: O43293 (Residues: 9-289; Coverage: 62%)
Gene names: DAPK3, ZIPK
Sequence domains: Protein kinase domain
Structure domains:

Ligands and Environments

2 bound ligands:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SLS BEAMLINE X10SA
Spacegroup: P21
Unit cell:
a: 33.549Å b: 90.68Å c: 41.464Å
α: 90° β: 100.45° γ: 90°
R-values:
R R work R free
0.146 0.143 0.187
Expression system: Escherichia coli