Structure analysis

Crystal Structure of KMD Phosphopeptide Bound to Human Class I MHC HLA-A2

X-ray diffraction
2.2Å resolution
Source organism: Homo sapiens
Assembly composition:
hetero trimer (preferred)
Entry contents: 3 distinct polypeptide molecules

Assemblies

Assembly 1 (preferred)
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Multimeric state: hetero trimer
Accessible surface area: 19088.51 Å2
Buried surface area: 4643.75 Å2
Dissociation area: 973.06 Å2
Dissociation energy (ΔGdiss): 11.41 kcal/mol
Dissociation entropy (TΔSdiss): 7.87 kcal/mol
Symmetry number: 1
PDBe Complex ID: PDB-CPX-137820

Macromolecules

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Chain: B
Length: 98 amino acids
Theoretical weight: 11.64 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P61769 (Residues: 22-119; Coverage: 99%)
Gene names: B2M, CDABP0092, HDCMA22P
Pfam: Immunoglobulin C1-set domain
InterPro:
CATH: Immunoglobulins
SCOP: C1 set domains (antibody constant domain-like)

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Chain: C
Length: 10 amino acids
Theoretical weight: 1.31 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
  • Canonical: Q86UW6 (Residues: 129-138; Coverage: 1%)
Gene names: B3BP, KIAA1413, N4BP2

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