› › Function and Biology

Crystal structure of Escherichia coli alaine racemase mutant P219A

Source organism: Escherichia coli K-12
Biochemical function: protein homodimerization activity
Biological process: cell wall organization
Cellular component: cytosol

Quick links

EC 5.1.1.1: Alanine racemase

Reaction catalysed:
L-alanine = D-alanine
Systematic name:
Alanine racemase
Alternative Name(s):
  • L-alanine racemase

GO terms

Sequence families

Pfam Protein families (Pfam)
PF00842
Domain description: Alanine racemase, C-terminal domain
Occurring in:
  1. Alanine racemase, biosynthetic
The deposited structure of PDB entry 3b8t contains 4 copies of Pfam domain PF00842 (Alanine racemase, C-terminal domain) in Alanine racemase, biosynthetic. Showing 1 copy in chain A.

PF01168
Domain description: Alanine racemase, N-terminal domain
Occurring in:
  1. Alanine racemase, biosynthetic
The deposited structure of PDB entry 3b8t contains 4 copies of Pfam domain PF01168 (Alanine racemase, N-terminal domain) in Alanine racemase, biosynthetic. Showing 1 copy in chain A.

InterPro InterPro annotations
IPR000821
Domain description: Alanine racemase
Occurring in:
  1. Alanine racemase, biosynthetic
IPR011079
Domain description: Alanine racemase, C-terminal
Occurring in:
  1. Alanine racemase, biosynthetic
IPR009006
Domain description: Alanine racemase/group IV decarboxylase, C-terminal
Occurring in:
  1. Alanine racemase, biosynthetic
IPR029066
Domain description: PLP-binding barrel
Occurring in:
  1. Alanine racemase, biosynthetic
IPR020622
Domain description: Alanine racemase, pyridoxal-phosphate attachment site
Occurring in:
  1. Alanine racemase, biosynthetic
IPR001608
Domain description: Alanine racemase, N-terminal
Occurring in:
  1. Alanine racemase, biosynthetic
IPR027417
Domain description: P-loop containing nucleoside triphosphate hydrolase
Occurring in:
  1. Alanine racemase, biosynthetic

Structure domains

CATH CATH domains
2.40.37.10
Class: Mainly Beta
Architecture: Beta Barrel
Topology: Lyase, Ornithine Decarboxylase; Chain A, domain 1
Homology: Lyase, Ornithine Decarboxylase; Chain A, domain 1
Occurring in:
  1. Alanine racemase, biosynthetic
The deposited structure of PDB entry 3b8t contains 4 copies of CATH domain 2.40.37.10 (Lyase, Ornithine Decarboxylase; Chain A, domain 1) in Alanine racemase, biosynthetic. Showing 1 copy in chain A.
3.20.20.10
Class: Alpha Beta
Architecture: Alpha-Beta Barrel
Topology: TIM Barrel
Homology: Alanine racemase
Occurring in:
  1. Alanine racemase, biosynthetic
The deposited structure of PDB entry 3b8t contains 4 copies of CATH domain 3.20.20.10 (TIM Barrel) in Alanine racemase, biosynthetic. Showing 1 copy in chain A.

Quick links