PDBe 3b7x

X-ray diffraction
2.1Å resolution

Crystal structure of human FK506-Binding Protein 6

Released:
Source organism: Homo sapiens
Entry authors: Walker JR, Davis T, Butler-Cole C, Paramanathan R, Weigelt J, Arrowsmith CH, Edwards AM, Bochkarev A, Dhe-Paganon S, Structural Genomics Consortium (SGC)

Function and Biology Details

Reaction catalysed:
Peptidylproline (omega=180) = peptidylproline (omega=0). 
Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Inactive peptidyl-prolyl cis-trans isomerase FKBP6 Chain: A
Molecule details ›
Chain: A
Length: 134 amino acids
Theoretical weight: 15.07 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: O75344 (Residues: 12-144; Coverage: 41%)
Gene names: FKBP36, FKBP6
Sequence domains: FKBP-type peptidyl-prolyl cis-trans isomerase
Structure domains: Chitinase A; domain 3

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: NSLS BEAMLINE X25
Spacegroup: I4122
Unit cell:
a: 55.059Å b: 55.059Å c: 229.965Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.258 0.256 0.282
Expression system: Escherichia coli BL21(DE3)