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Crystal structure of Human Brain-type Creatine Kinase

X-ray diffraction
2Å resolution
PDB entry 3b6r coloured by chain, front view.
PDB entry 3b6r coloured by chain, side view.
PDB entry 3b6r coloured by chain, top view.
Source organism: Homo sapiens
Assembly composition:
homo dimer (preferred)
Entry contents: 1 distinct polypeptide molecule

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Assemblies

Assembly 1 (preferred)
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Assembly Name: Creatine kinase B-type
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Multimeric state: homo dimer
Accessible surface area: 30814.96 Å2
Buried surface area: 3095.2 Å2
Dissociation area: 614.39 Å2
Dissociation energy (ΔGdiss): -8.35 kcal/mol
Dissociation entropy (TΔSdiss): 13.54 kcal/mol
Symmetry number: 1
PDBe Complex ID: PDB-CPX-146122

Macromolecules

Creatine kinase B-type
Chains: A, B
Length: 381 amino acids
Theoretical weight: 42.7 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P12277 (Residues: 1-381; Coverage: 100%)
Gene names: CKB, CKBB
Pfam:
InterPro:
CATH:
Creatine kinase B-type in PDB entry 3b6r, assembly 1, front view.
Creatine kinase B-type in PDB entry 3b6r, assembly 1, side view.
Creatine kinase B-type in PDB entry 3b6r, assembly 1, top view.
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