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Structure of E163K/R145E DJ-1

X-ray diffraction
1.5Å resolution
PDB entry 3b3a coloured by chain, front view.
PDB entry 3b3a coloured by chain, side view.
PDB entry 3b3a coloured by chain, top view.
Source organism: Homo sapiens
Assembly composition:
homo dimer (preferred)
Entry contents: 1 distinct polypeptide molecule

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Assemblies

Assembly 1 (preferred)
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Assembly Name: Parkinson disease protein 7
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Multimeric state: homo dimer
Accessible surface area: 14532.41 Å2
Buried surface area: 4396.39 Å2
Dissociation area: 1,358.11 Å2
Dissociation energy (ΔGdiss): 10.87 kcal/mol
Dissociation entropy (TΔSdiss): 12.38 kcal/mol
Symmetry number: 2
PDBe Complex ID: PDB-CPX-189207

Macromolecules

Parkinson disease protein 7
Chain: A
Length: 192 amino acids
Theoretical weight: 20.17 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q99497 (Residues: 1-189; Coverage: 100%)
Gene name: PARK7
Pfam: DJ-1/PfpI family
InterPro:
CATH: Rossmann fold
Parkinson disease protein 7 in PDB entry 3b3a, assembly 1, front view.
Parkinson disease protein 7 in PDB entry 3b3a, assembly 1, side view.
Parkinson disease protein 7 in PDB entry 3b3a, assembly 1, top view.
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