Assemblies
Assembly Name:
Fibroblast growth factor receptor 2
Multimeric state:
homo tetramer
Accessible surface area:
44342.4 Å2
Buried surface area:
16799.72 Å2
Dissociation area:
2,972.35
Å2
Dissociation energy (ΔGdiss):
21.58
kcal/mol
Dissociation entropy (TΔSdiss):
15.26
kcal/mol
Symmetry number:
4
PDBe Complex ID:
PDB-CPX-149431
Assembly Name:
Fibroblast growth factor receptor 2
Multimeric state:
homo dimer
Accessible surface area:
25019.41 Å2
Buried surface area:
5545.52 Å2
Dissociation area:
1,730.87
Å2
Dissociation energy (ΔGdiss):
15.69
kcal/mol
Dissociation entropy (TΔSdiss):
13.73
kcal/mol
Symmetry number:
2
PDBe Complex ID:
PDB-CPX-149430
Macromolecules
Chains: A, B
Length: 311 amino acids
Theoretical weight: 35.65 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
Pfam: Protein tyrosine and serine/threonine kinase
InterPro:
Length: 311 amino acids
Theoretical weight: 35.65 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
- Canonical:
P21802 (Residues: 458-768; Coverage: 39%)
Pfam: Protein tyrosine and serine/threonine kinase
InterPro:
- Protein kinase-like domain superfamily
- Protein kinase domain
- Serine-threonine/tyrosine-protein kinase, catalytic domain
- Protein kinase, ATP binding site
- Tyrosine-protein kinase, active site
