PDBe 3ap4

X-ray diffraction
2.33Å resolution

Crystal structure of the galectin-8 N-terminal carbohydrate recognition domain in complex with lactose

Source organism: Homo sapiens

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Galectin-8 Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 154 amino acids
Theoretical weight: 17.42 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
  • Canonical: O00214 (Residues: 1-154; Coverage: 49%)
Gene name: LGALS8
Sequence domains: Galactoside-binding lectin
Structure domains: Jelly Rolls

Ligands and Environments

1 bound ligand:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SPRING-8 BEAMLINE BL38B1
Spacegroup: P1
Unit cell:
a: 41.528Å b: 64.888Å c: 71.584Å
α: 98.41° β: 105.49° γ: 108.66°
R R work R free
0.194 0.191 0.251
Expression system: Escherichia coli