PDBe 3a99

X-ray diffraction
1.6Å resolution

Structure of PIM-1 kinase crystallized in the presence of P27KIP1 Carboxy-terminal peptide

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Serine/threonine-protein kinase pim-1 Chain: A
Molecule details ›
Chain: A
Length: 320 amino acids
Theoretical weight: 36.48 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P11309 (Residues: 106-404; Coverage: 74%)
  • Best match: P11309-2 (Residues: 15-313)
Gene name: PIM1
Sequence domains: Protein kinase domain
Structure domains:

Ligands and Environments

2 bound ligands:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SPRING-8 BEAMLINE BL26B2
Spacegroup: P65
Unit cell:
a: 98.156Å b: 98.156Å c: 80.296Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.187 0.187 0.206
Expression system: Escherichia coli