PDBe 3a8x

X-ray diffraction
2Å resolution

Crystal Structure of PKCiota kinase domain

Released:

Function and Biology Details

Structure analysis Details

Assemblies composition:
monomeric (preferred)
homo dimer
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Protein kinase C iota type Chains: A, B
Molecule details ›
Chains: A, B
Length: 345 amino acids
Theoretical weight: 39.85 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
UniProt:
  • Canonical: P41743 (Residues: 249-588; Coverage: 57%)
Gene names: DXS1179E, PRKCI
Sequence domains:
Structure domains:

Ligands and Environments

1 bound ligand:

1 modified residue:

Experiments and Validation Details

Entry percentile scores
X-ray source: PHOTON FACTORY BEAMLINE BL-5A
Spacegroup: C2221
Unit cell:
a: 84.896Å b: 89.153Å c: 204.265Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.225 0.223 0.271
Expression system: Spodoptera frugiperda