Function and Biology Details
The C-O-P bond 3' to the apurinic or apyrimidinic site in DNA is broken by a beta-elimination reaction, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.
Hydrolysis of DNA containing ring-opened 7-methylguanine residues, releasing 2,6-diamino-4-hydroxy-5-(N-methyl)formamidopyrimidine.
- not assigned
Structure analysis Details
Length: 295 amino acids
Theoretical weight: 34.58 KDa
Source organism: Acanthamoeba polyphaga mimivirus
Expression system: Escherichia coli
- Canonical: Q5UQ00 (Residues: 1-287; Coverage: 100%)
- Formamidopyrimidine-DNA glycosylase H2TH domain
- Formamidopyrimidine-DNA glycosylase N-terminal domain