PDBe 3a2q

X-ray diffraction
1.8Å resolution

Structure of 6-aminohexanoate cyclic dimer hydrolase complexed with substrate

Released:

Function and Biology Details

Reaction catalysed:
1,8-diazacyclotetradecane-2,9-dione + H(2)O = N-(6-aminohexanoyl)-6-aminohexanoate
Biochemical function:
Biological process:
Cellular component:
  • not assigned

Structure analysis Details

Assemblies composition:
monomeric (preferred)
homo dimer
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
6-aminohexanoate-cyclic-dimer hydrolase Chain: A
Molecule details ›
Chain: A
Length: 493 amino acids
Theoretical weight: 52.25 KDa
Source organism: Arthrobacter sp. KI72
Expression system: Escherichia coli
UniProt:
  • Canonical: P13398 (Residues: 1-493; Coverage: 100%)
Gene name: nylA
Sequence domains: Amidase
Structure domains: Amidase signature (AS) domain

Ligands and Environments

2 bound ligands:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SPRING-8 BEAMLINE BL41XU
Spacegroup: P62
Unit cell:
a: 130.66Å b: 130.66Å c: 58.63Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.187 0.187 0.222
Expression system: Escherichia coli