PDBe 3zm1

X-ray diffraction
1.4Å resolution

Function and Biology Details

Reaction catalysed:
Protein tyrosine phosphate + H(2)O = protein tyrosine + phosphate
Biological process:
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Tyrosine-protein phosphatase non-receptor type 11 Chain: A
Molecule details ›
Chain: A
Length: 284 amino acids
Theoretical weight: 33.11 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q06124 (Residues: 248-531; Coverage: 47%)
  • Best match: Q06124-2 (Residues: 248-527)
Gene names: PTP2C, PTPN11, SHPTP2
Sequence domains: Protein-tyrosine phosphatase
Structure domains: Protein tyrosine phosphatase superfamily

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: BESSY BEAMLINE 14.1
Spacegroup: P1
Unit cell:
a: 40.174Å b: 42.051Å c: 49.256Å
α: 72° β: 80.28° γ: 74.19°
R-values:
R R work R free
0.172 0.17 0.203
Expression system: Escherichia coli BL21(DE3)