PDBe 3zfl

X-ray diffraction
1.88Å resolution

Crystal structure of the V58A mutant of human class alpha glutathione transferase in the apo form

Released:
Source organism: Homo sapiens
Entry authors: Parbhoo N, Fanucchi S, Achilonu IA, Fernandes MA, Gildenhuys S, Dirr HW

Function and Biology Details

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Glutathione S-transferase A1 Chains: A, B
Molecule details ›
Chains: A, B
Length: 222 amino acids
Theoretical weight: 25.64 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P08263 (Residues: 1-222; Coverage: 100%)
Gene name: GSTA1
Sequence domains:
Structure domains:

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: BRUKER X8 PROTEUM
Spacegroup: C2
Unit cell:
a: 99.893Å b: 93.283Å c: 51.573Å
α: 90° β: 93.12° γ: 90°
R-values:
R R work R free
0.221 0.218 0.289
Expression system: Escherichia coli BL21(DE3)