PDBe 3wwt

X-ray diffraction
2Å resolution

Crystal Structure of the Y3:STAT1ND complex

Source organisms:
Entry authors: Sakaguchi T, Oda K, Matoba Y

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero tetramer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Signal transducer and activator of transcription 1-alpha/beta Chain: A
Molecule details ›
Chain: A
Length: 139 amino acids
Theoretical weight: 17.16 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
  • Canonical: P42224 (Residues: 1-126; Coverage: 17%)
Gene name: STAT1
Sequence domains: STAT protein, protein interaction domain
Structure domains: STAT transcription factor, N-terminal domain
C' protein Chain: B
Molecule details ›
Chain: B
Length: 119 amino acids
Theoretical weight: 14.56 KDa
Source organism: Sendai virus (Z)
Expression system: Escherichia coli
  • Canonical: P04862 (Residues: 109-215; Coverage: 50%)
Gene name: P/V/C

Ligands and Environments

1 bound ligand:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SPRING-8 BEAMLINE BL38B1
Spacegroup: P6522
Unit cell:
a: 72.27Å b: 72.27Å c: 197.15Å
α: 90° β: 90° γ: 120°
R R work R free
0.229 0.229 0.27
Expression system: Escherichia coli