PDBe 3wup

X-ray diffraction
1.6Å resolution

Crystal Structure of the Ubiquitin-Binding Zinc Finger (UBZ) Domain of the Human DNA Polymerase Eta

Released:

Function and Biology Details

Reaction catalysed:
Deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1). 
Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assemblies composition:
monomeric (preferred)
homo trimer
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
DNA polymerase eta Chain: A
Molecule details ›
Chain: A
Length: 38 amino acids
Theoretical weight: 4.4 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q9Y253 (Residues: 630-665; Coverage: 5%)
Gene names: POLH, RAD30, RAD30A, XPV

Ligands and Environments


No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: PHOTON FACTORY BEAMLINE BL-5A
Spacegroup: P213
Unit cell:
a: 49.188Å b: 49.188Å c: 49.188Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.171 0.169 0.226
Expression system: Escherichia coli