PDBe 3w5k

X-ray diffraction
2.6Å resolution

Crystal structure of Snail1 and importin beta complex

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Importin subunit beta-1 Chain: A
Molecule details ›
Chain: A
Length: 876 amino acids
Theoretical weight: 97.26 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q14974 (Residues: 1-876; Coverage: 100%)
Gene names: KPNB1, NTF97
Sequence domains:
Zinc finger protein SNAI1 Chain: B
Molecule details ›
Chain: B
Length: 264 amino acids
Theoretical weight: 29.12 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: O95863 (Residues: 1-264; Coverage: 100%)
Gene names: SNAH, SNAI1
Sequence domains:

Ligands and Environments

1 bound ligand:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SPRING-8 BEAMLINE BL44XU, PAL/PLS BEAMLINE 6C1
Spacegroup: C2
Unit cell:
a: 228.21Å b: 77.528Å c: 72.019Å
α: 90° β: 100.96° γ: 90°
R-values:
R R work R free
0.217 0.215 0.264
Expression system: Escherichia coli