PDBe 3w59

X-ray diffraction
2.1Å resolution

Crystal structure of Galectin-1 in the lactose-unbound state(P212121)

Released:
Source organism: Homo sapiens
Entry authors: Saburi H, Tanaka T, Kunishima N

Function and Biology Details

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Galectin-1 Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 134 amino acids
Theoretical weight: 14.6 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P09382 (Residues: 2-135; Coverage: 99%)
Gene name: LGALS1
Sequence domains: Galactoside-binding lectin
Structure domains: Jelly Rolls

Ligands and Environments

3 bound ligands:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SPRING-8 BEAMLINE BL26B2
Spacegroup: P212121
Unit cell:
a: 58.14Å b: 111.557Å c: 117.192Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.212 0.212 0.231
Expression system: Escherichia coli