PDBe 3vtv

X-ray diffraction
1.7Å resolution

Crystal structure of Optineurin LIR-fused human LC3B_2-119

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Microtubule-associated proteins 1A/1B light chain 3B; Optineurin Chain: A
Molecule details ›
Chain: A
Length: 134 amino acids
Theoretical weight: 15.66 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q9GZQ8 (Residues: 2-119; Coverage: 94%)
  • Canonical: Q96CV9 (Residues: 170-181; Coverage: 2%)
  • nullnull
Gene names: FIP2, GLC1E, HIP7, HYPL, MAP1ALC3, MAP1LC3B, NRP, OPTN
Structure domains: Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, domain 1

Ligands and Environments

1 bound ligand:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SPRING-8 BEAMLINE BL41XU
Spacegroup: P212121
Unit cell:
a: 35.2Å b: 53Å c: 60.96Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.194 0.192 0.252
Expression system: Escherichia coli