PDBe 3vln

X-ray diffraction
1.7Å resolution

Human Glutathione Transferase O1-1 C32S Mutant in Complex with Ascorbic Acid

Released:

Function and Biology Details

Reactions catalysed:
2 glutathione + dehydroascorbate = glutathione disulfide + ascorbate
RX + glutathione = HX + R-S-glutathione
Methylarsonate + 2 glutathione = methylarsonite + glutathione disulfide + H(2)O
Biochemical function:
Cellular component:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Glutathione S-transferase omega-1 Chain: A
Molecule details ›
Chain: A
Length: 241 amino acids
Theoretical weight: 27.58 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P78417 (Residues: 1-241; Coverage: 100%)
Gene names: GSTO1, GSTTLP28
Sequence domains:
Structure domains:

Ligands and Environments


No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: AUSTRALIAN SYNCHROTRON BEAMLINE MX2
Spacegroup: P3121
Unit cell:
a: 56.918Å b: 56.918Å c: 140.511Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.182 0.18 0.217
Expression system: Escherichia coli