PDBe 3vf0

X-ray diffraction
2.54Å resolution

Raver1 in complex with metavinculin L954 deletion mutant

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Vinculin Chain: A
Molecule details ›
Chain: A
Length: 283 amino acids
Theoretical weight: 31.12 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21
UniProt:
  • Canonical: P18206 (Residues: 855-1134; Coverage: 25%)
Gene name: VCL
Sequence domains: Vinculin family
Structure domains: Four Helix Bundle (Hemerythrin (Met), subunit A)
Ribonucleoprotein PTB-binding 1 Chain: B
Molecule details ›
Chain: B
Length: 285 amino acids
Theoretical weight: 31.65 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21
UniProt:
  • Canonical: Q8IY67 (Residues: 39-321; Coverage: 47%)
Gene names: KIAA1978, RAVER1
Sequence domains: RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
Structure domains: Alpha-Beta Plaits

Ligands and Environments

2 bound ligands:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 19-ID
Spacegroup: P6522
Unit cell:
a: 164.905Å b: 164.905Å c: 102.594Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.17 0.168 0.205
Expression system: Escherichia coli BL21