PDBe 3v8x

X-ray diffraction
2.6Å resolution

The crystal structure of transferrin binding protein A (TbpA) from Neisserial meningitidis serogroup B in complex with full length human transferrin

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Transferrin-binding protein 1 Chain: A
Molecule details ›
Chain: A
Length: 904 amino acids
Theoretical weight: 101.21 KDa
Source organism: Neisseria meningitidis serogroup B
Expression system: Escherichia coli
UniProt:
  • Canonical: Q9K0U9 (Residues: 25-915; Coverage: 100%)
Gene names: NMB0461, tbp1
Sequence domains:
Structure domains:
Serotransferrin Chain: B
Molecule details ›
Chain: B
Length: 698 amino acids
Theoretical weight: 77.15 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
  • Canonical: P02787 (Residues: 1-698; Coverage: 100%)
Gene names: PRO1400, TF
Sequence domains: Transferrin
Structure domains: Periplasmic binding protein-like II

Ligands and Environments


No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 22-ID
Spacegroup: P212121
Unit cell:
a: 91.014Å b: 129.362Å c: 198.589Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.211 0.208 0.267
Expression systems:
  • Escherichia coli
  • Not provided