PDBe 3v89

X-ray diffraction
3.1Å resolution

The crystal structure of transferrin binding protein A (TbpA) from Neisseria meningitidis serogroup B in complex with the C-lobe of human transferrin

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Transferrin-binding protein 1 Chain: A
Molecule details ›
Chain: A
Length: 904 amino acids
Theoretical weight: 101.18 KDa
Source organism: Neisseria meningitidis serogroup B
Expression system: Escherichia coli
UniProt:
  • Canonical: Q9K0U9 (Residues: 25-915; Coverage: 100%)
Gene names: NMB0461, tbp1
Sequence domains:
Structure domains:
Serotransferrin Chain: B
Molecule details ›
Chain: B
Length: 343 amino acids
Theoretical weight: 38.2 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
  • Canonical: P02787 (Residues: 356-698; Coverage: 51%)
Gene names: PRO1400, TF
Sequence domains: Transferrin

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 22-ID
Spacegroup: P21
Unit cell:
a: 58.054Å b: 107.592Å c: 130.719Å
α: 90° β: 94.48° γ: 90°
R-values:
R R work R free
0.227 0.224 0.287
Expression systems:
  • Escherichia coli
  • Not provided