PDBe 3u2j

Neutron Diffraction
2Å resolution

Neutron crystal structure of human Transthyretin

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
homo tetramer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Transthyretin Chains: A, B
Molecule details ›
Chains: A, B
Length: 117 amino acids
Theoretical weight: 12.89 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P02766 (Residues: 32-147; Coverage: 91%)
Gene names: PALB, TTR
Sequence domains: HIUase/Transthyretin family
Structure domains: Transthyretin/hydroxyisourate hydrolase domain

Ligands and Environments

1 bound ligand:

No modified residues

Experiments and Validation Details

Spacegroup: P21212
Unit cell:
a: 44.094Å b: 86.103Å c: 66.313Å α: 90° β: 90° γ: 90°
R-values:
R R work R free 0.234 0.232 0.272
Expression system: Escherichia coli