PDBe 3u2i

X-ray diffraction
1.7Å resolution

X-ray crystal structure of human Transthyretin at room temperature

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
homo tetramer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Transthyretin Chains: A, B
Molecule details ›
Chains: A, B
Length: 117 amino acids
Theoretical weight: 12.89 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P02766 (Residues: 32-147; Coverage: 91%)
Gene names: PALB, TTR
Sequence domains: HIUase/Transthyretin family
Structure domains: Transthyretin/hydroxyisourate hydrolase domain

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: MACSCIENCE
Spacegroup: P21212
Unit cell:
a: 43.431Å b: 86.368Å c: 65.716Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.197 0.195 0.239
Expression system: Escherichia coli