PDBe 3tvc

X-ray diffraction
2.43Å resolution

Human MMP13 in complex with L-glutamate motif inhibitor

Released:

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Collagenase 3 Chain: A
Molecule details ›
Chain: A
Length: 169 amino acids
Theoretical weight: 19.02 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P45452 (Residues: 104-272; Coverage: 37%)
Gene name: MMP13
Sequence domains: Matrixin
Structure domains: Collagenase (Catalytic Domain)

Ligands and Environments


No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID23-1
Spacegroup: P21212
Unit cell:
a: 60.303Å b: 85.16Å c: 40.916Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.165 0.162 0.234
Expression system: Escherichia coli