PDBe 3t7u

X-ray diffraction
2.9Å resolution

A NeW Crystal structure of APC-ARM

Released:
Source organism: Homo sapiens

Function and Biology Details

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Adenomatous polyposis coli protein Chains: A, B
Molecule details ›
Chains: A, B
Length: 378 amino acids
Theoretical weight: 42.05 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P25054 (Residues: 407-775; Coverage: 13%)
Gene names: APC, DP2.5
Sequence domains: Armadillo/beta-catenin-like repeat
Structure domains: Leucine-rich Repeat Variant

Ligands and Environments

1 bound ligand:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRF BEAMLINE BL17U
Spacegroup: P31
Unit cell:
a: 72.496Å b: 72.496Å c: 129.981Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.271 0.269 0.313
Expression system: Escherichia coli