PDBe 3t7m

X-ray diffraction
1.8Å resolution

Crystal Structure of Human Glycogenin-1 (GYG1) complexed with manganese and UDP, in a triclinic closed form

Released:
Source organism: Homo sapiens

Function and Biology Details

Reaction catalysed:
UDP-alpha-D-glucose + glycogenin = UDP + alpha-D-glucosylglycogenin
Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Glycogenin-1 Chains: A, B
Molecule details ›
Chains: A, B
Length: 263 amino acids
Theoretical weight: 29.61 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P46976 (Residues: 1-262; Coverage: 75%)
Gene names: GYG, GYG1
Sequence domains: Glycosyl transferase family 8
Structure domains: Spore Coat Polysaccharide Biosynthesis Protein SpsA; Chain A

Ligands and Environments

3 bound ligands:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU FR-E SUPERBRIGHT
Spacegroup: P1
Unit cell:
a: 47.006Å b: 47.081Å c: 70.02Å
α: 87.89° β: 78.88° γ: 76.65°
R-values:
R R work R free
0.192 0.189 0.243
Expression system: Escherichia coli BL21(DE3)