PDBe 3t7l

X-ray diffraction
1.09Å resolution

Crystal structure of the FYVE domain of endofin (ZFYVE16) at 1.1A resolution

Released:
Source organism: Homo sapiens
Entry authors: Chaikuad A, Williams E, Guo K, Sanvitale C, Berridge G, Krojer T, Muniz JRC, Canning P, Phillips C, Shrestha A, von Delft F, Weigelt J, Arrowsmith CH, Edwards AM, Bountra C, Bullock A, Structural Genomics Consortium (SGC)

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Zinc finger FYVE domain-containing protein 16 Chain: A
Molecule details ›
Chain: A
Length: 90 amino acids
Theoretical weight: 10.24 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q7Z3T8 (Residues: 733-820; Coverage: 6%)
Gene names: KIAA0305, ZFYVE16
Sequence domains: FYVE zinc finger
Structure domains: Zinc/RING finger domain, C3HC4 (zinc finger)

Ligands and Environments

2 bound ligands:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: DIAMOND BEAMLINE I04
Spacegroup: P43212
Unit cell:
a: 42.944Å b: 42.944Å c: 76.879Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.168 0.142 0.154
Expression system: Escherichia coli